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5 results tagged comments  ✕   ✕
Encoding ASCII in DNA - a proposal for a standard https://www.aleph.se/Trans/Individual/Body/ascii.html
Mon 20 Jun 2022 02:24:43 PM PDT archive.org

Once we start editing DNA on a large scale, we will need to keep track of what we do, revision histories, comment the new genes and add copyright notices. This is a suggested standard of entering ASCII information into the genome:

We will use 4-base codons to encode 7-bit ASCII. I know it is a bit primitive, but I think it does well enough and we might want to use the extra bit (see below). Each base codes two bits, and the complementary base codes the inverse:

A: 00 G: 01 C: 10 T: 11

Thus each character will be coded as four bases, read in the canonical 5'->3' direction.

The letters 'DNA' will thus become

01000100 01001110 01000001
 G A G A  G A T C  G A A G

or GAGAGATCGAAG.

The problem when reading a DNA string is: which strand should we read? If we read the complementary strand, we will get an inverted string backwards. But since we use 7-bit ascii, we can test to see if every 8th bit is a one or zero, and deduce which side we are on. The reading process thus tries out the eight starting frames, and chooses the one which gives an unbroken stretch of ones or zeros. If the stretch are zeros, the bases are read and converted, if they are ones they are read to the end of the message, inverted and reversed. Note that some errors can become detectable this way, as interruptions of the stretches of similar bits.

To delineate the comments, we need markers. A standard could be the sequence corresponding to "COMMENT COMMENT COMMENT..." repeated a number of times (we don't want to use a long stretch of similar bases, since it would influence the bending of DNA, which might lead to unwanted effects).

A problem is that we might accidentally create active regions in the DNA with these comments; ideally we should choose a coding that minimizes the biological effects of the comment. Methylating the cytosine bases will also inactivate the comment. If it can be marked as an intron it could also be placed inside exons, making sure the comment will follow the gene it belongs to.

Thanks to John D. Gleason for the methylating and intron ideas.

dna ascii encoding text comments
GitHub - panicsteve/shutup-css: CSS stylesheet to hide comments on web pages https://github.com/panicsteve/shutup-css
Tue 08 Dec 2020 12:18:37 AM PST archive.org
css comments browser
Loklak Search - Distributed Open Source Search for Twitter and Social Media with Peer to Peer Technology https://loklak.org/
Mon 21 Jan 2019 07:06:16 PM PST archive.org

An open source search engine for social media, by one of the developers of YaCy. Can monitor Twitter, Youtube, Github,

Can return JSON as well as RSS for search results.

API: https://api.loklak.org/

Source code: https://github.com/loklak/loklak_server

foss searchengine socialmedia comments java
tessalt/echo-chamber-js ยท GitHub https://github.com/tessalt/echo-chamber-js
Tue 20 Mar 2018 12:23:10 AM PDT archive.org

A bit of JavaScript that looks, as far as anyone can tell, like the Disqus commenting plugin. It actually stores comments in the commentor's browser's local storage and nowhere else. They think they left a comment but no one else will ever see it. Goddamn brilliant.

javascript comments localstorage webdesign trolling
Directory Contents http://files.pushshift.io/reddit/comments/
Mon 19 Mar 2018 10:12:03 PM PDT archive.org

Much more up to date archive of reddit comments, updated daily as well as monthly. No rss feed but I should be able to create one someplace.

nlp reddit comments corpus data archives
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